WWC1 抗体 (AA 990-1080)
Quick Overview for WWC1 抗体 (AA 990-1080) (ABIN7602724)
抗原
See all WWC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 990-1080
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原理
- Anti-KIBRA/WWC1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-KIBRA/WWC1 Antibody Picoband® (ABIN7602724). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KIBRA/WWC1 recombinant protein (Position: D990-Q1080).
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亚型
- IgG
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anti-WW and C2 Domain Containing 1 (WWC1) (AA 847-1094) antibody
WWC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) (AA 950-1050) antibodyWWC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) (AA 351-450) antibodyWWC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) antibodyWWC1 适用: 人 WB 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) antibodyWWC1 适用: 人 WB 宿主: 小鼠 Monoclonal 1H8 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Buther, K., Plaas, C., Barnekow, A., Kremerskothen, J. KIBRA is a novel substrate for protein kinase C-zeta. Biochem. Biophys. Res. Commun. 317: 703-707, 2004. 2. Duning, K., Wennmann, D. O., Bokemeyer, A., Reissner, C., Wershching, H., Thomas, C., Buschert, J., Guske, K., Franzke, V., Floel, A., Lohmann, H., Knecht, S., and 13 others. Common exonic missense variants in the C2 domain of the human KIBRA protein modify lipid binding and cognitive performance. Transl. Psychiat. 3: e272, 2013. Note: Electronic Article. 3. Kremerskothen, J., Plaas, C., Buther, K., Finger, I., Veltel, S., Matanis, T., Liedtke, T., Barnekow, A. Characterization of KIBRA, a novel WW domain-containing protein. Biochem. Biophys. Res. Commun. 300: 862-867, 2003. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- WWC1 (WW and C2 Domain Containing 1 (WWC1))
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别名
- WWC1
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背景
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Synonyms: Elongator complex protein 3, Help3, ELP3
Tissue Specificity: Expressed at low levels in the more differentiated suprabasal regions of the small intestine, and at higher levels in the colon, mainly in the upper region and in scattered cells throughout the remaining epithelium. Also expressed in epithelial cells of bladder, ileum and stomach and at lower levels in pancreas and earskin. The phosphorylated form is nearly exclusively expressed in goblet cells of the small intestine and in the lumen-proximal cells of the colon (at protein level). Also expressed in jejunum and duodenum.
Background: Protein KIBRA also known as kidney and brain expressed protein (KIBRA) or WW domain-containing protein 1 (WWC1) is a protein that in humansl is encoded by the WWC1 gene. The protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that enhance memory in some individuals. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 130 kDa
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基因ID
- 23286
抗原
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