APOA5 抗体 (AA 99-217)
Quick Overview for APOA5 抗体 (AA 99-217) (ABIN7602720)
抗原
See all APOA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 99-217
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原理
- Anti-Apolipoprotein A V/APOA5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Apolipoprotein A V/APOA5 Antibody Picoband® (ABIN7602720). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Apolipoprotein A V/APOA5 recombinant protein (Position: E99-A217).
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亚型
- IgG
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anti-Apolipoprotein A-V (APOA5) (AA 167-335) antibody
APOA5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-V (APOA5) (AA 167-335) antibodyAPOA5 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Apolipoprotein A-V (APOA5) (AA 21-210) antibodyAPOA5 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-V (APOA5) (AA 21-210) antibodyAPOA5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Apolipoprotein A-V (APOA5) antibodyAPOA5 适用: 人 ELISA, ICC 宿主: 小鼠 Multiclonal 2G1H11-HRP-1F1E8 unconjugated
anti-Apolipoprotein A-V (APOA5) antibodyAPOA5 适用: 人, 大鼠, 小鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-V (APOA5) (AA 1-366) antibodyAPOA5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Apolipoprotein A-V (APOA5) (N-Term) antibodyAPOA5 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-V (APOA5) (AA 207-366) antibodyAPOA5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-V (APOA5) (AA 169-367) antibodyAPOA5 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1.Caussy, C., Charriere, S., Marcais, C., Di Filippo, M., Sassolas, A., Delay, M., Euthine, V., Jalabert, A., Lefai, E., Rome, S., Moulin, P. An APOA5 3-prime UTR variant associated with plasma triglycerides triggers APOA5 downregulation by creating a functional miR-485-5p binding site. Am. J. Hum. Genet. 94: 129-134, 2014. 2.Do, R., Stitziel, N. O., Won, H.-H., Berg Jorgensen, A., Duga, S., Merlini, P. A., Kiezun, A., Farrall, M., Goel, A., Zuk, O., Guella, I., Asselta, R., and 82 others. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature 518: 102-106, 2015. 3.Endo, K., Yanagi, H., Araki, J., Hirano, C., Yamakawa-Kobayashi, K., Tomura, S. Association found between the promoter region polymorphism in the apolipoprotein A-V gene and the serum triglyceride level in Japanese schoolchildren. Hum. Genet. 111: 570-572, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- APOA5 (Apolipoprotein A-V (APOA5))
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别名
- APOA5
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背景
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Synonyms: P-selectin, CD62 antigen-like family member P, Granule membrane protein 140, GMP-140, Leukocyte-endothelial cell adhesion molecule 3, LECAM3, Platelet activation dependent granule-external membrane protein, PADGEM, CD62P, Selp, Grmp
Tissue Specificity: Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Background: Apolipoprotein A-V is a protein that in humans is encoded by the APOA5 gene. The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified.
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分子量
- 45 kDa
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基因ID
- 116519
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UniProt
- Q6Q788
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途径
- Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
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