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CES1 抗体 (AA 99-206)

This anti-CES1 antibody is a 小鼠 单克隆 antibody detecting CES1 in WB, IHC, ICC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602719
发货至: 中国

Quick Overview for CES1 抗体 (AA 99-206) (ABIN7602719)

抗原

See all CES1 抗体
CES1 (Carboxylesterase 1 (CES1))

适用

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人, 小鼠, 大鼠

宿主

  • 38
  • 5
  • 1
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小鼠

克隆类型

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  • 5
单克隆

标记

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This CES1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

3F10
  • 抗原表位

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    AA 99-206

    原理

    Anti-Liver Carboxylesterase 1/CES1 Antibody Picoband® (monoclonal, 3F10)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Liver Carboxylesterase 1/CES1 Antibody Picoband® (monoclonal, 3F10) (ABIN7602719). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Liver Carboxylesterase 1/CES1 recombinant protein (Position: E99-A206).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. "Entrez Gene: CES1 carboxylesterase 1 (monocyte/macrophage serine esterase 1)". 2. Markey GM (Feb 2011). "Carboxylesterase 1 (Ces1): from monocyte marker to major player". J Clin Pathol. 64 (2): 107-9. 3. Zhu HJ, Appel DI, Johnson JA, Chavin KD, Markowitz JS (Jan 2009). "Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril". Biochem Pharmacol. 77 (7): 1266-72.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CES1 (Carboxylesterase 1 (CES1))

    别名

    CES1

    背景

    Synonyms: Fatty acid-binding protein, heart, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, H-FABP, Fabp3

    Tissue Specificity: Heart, but also skeletal muscle, kidney, brain and mammary gland.

    Background: Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene. This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

    分子量

    63 kDa

    基因ID

    1066

    UniProt

    P23141

    途径

    Monocarboxylic Acid Catabolic Process
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