SERAC1 抗体 (AA 97-623)
Quick Overview for SERAC1 抗体 (AA 97-623) (ABIN7602709)
抗原
See all SERAC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 97-623
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原理
- Anti-SERAC1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SERAC1 Antibody Picoband® (ABIN7602709). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SERAC1 recombinant protein (Position: E97-H623).
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亚型
- IgG
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anti-Serine Active Site Containing 1 (SERAC1) (AA 41-64), (N-Term) antibody
SERAC1 适用: 人 WB 宿主: 兔 Polyclonal RB50081 unconjugated
anti-Serine Active Site Containing 1 (SERAC1) (AA 176-225) antibodySERAC1 适用: 人, 大鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Serine Active Site Containing 1 (SERAC1) (AA 552-581), (C-Term) antibodySERAC1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB28676 unconjugated
anti-Serine Active Site Containing 1 (SERAC1) (AA 555-585), (C-Term) antibodySERAC1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 7/17/2012. 2. Lumish, H. S., Yang, Y., Xia, F., Wilson, A., Chung, W. K. The expanding MEGDEL phenotype: optic nerve atrophy, microcephaly, and myoclonic epilepsy in a child with SERAC1 mutations. JIMD Rep. 16: 75-79, 2014. 3. Maas, R. R., Iwanicka-Pronicka, K., Kalkan Ucar, S., Alhaddad, B., AlSayed, M., Al-Owain, M. A., Al-Zaidan, H. I., Balasubramaniam, S., Baric, I., Bubshait, D. K., Burlina, A., Christodoulou, J., and 46 others. Progressive deafness-dystonia due to SERAC1 mutations: a study of 67 cases. Ann. Neurol. 82: 1004-1015, 2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SERAC1 (Serine Active Site Containing 1 (SERAC1))
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别名
- SERAC1
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背景
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Synonyms: FERM domain-containing protein 6, Willin, FRMD6, C14orf31
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endoplasmic reticula, where it mediates phospholipid exchange. The encoded protein plays a major role in mitochondrial function and intracellular cholesterol trafficking. Defects in this gene are a cause of 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (MEGDEL). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
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分子量
- 74, 20 kDa
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基因ID
- 84947
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途径
- Inositol Metabolic Process
抗原
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