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POMGNT1 抗体 (AA 96-394)

POMGNT1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602699
发货至: 中国
  • 抗原 See all POMGNT1 抗体
    POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 96-394
    适用
    • 12
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 10
    • 2
    克隆类型
    • 10
    • 2
    多克隆
    标记
    • 8
    • 2
    • 1
    • 1
    This POMGNT1 antibody is un-conjugated
    应用范围
    • 7
    • 7
    • 4
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    Anti-POMGNT1 Antibody Picoband®
    产品特性
    Anti-POMGNT1 Antibody Picoband® (ABIN7602699). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human POMGNT1 recombinant protein (Position: R96-E394). Human POMGNT1 shares 99.7% amino acid (aa) sequence identity with both mouse and rat POMGNT1.
    Top Product
    Discover our top product POMGNT1 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Biancheri, R., Bertini, E., Falace, A., Pedemonte, M., Rossi, A., D'Amico, A., Scapolan, S., Bergamino, L., Petrini, S., Cassandrini, D., Broda, P., Manfredi, M., Zara, F., Santorelli, F. M., Minetti, C., Bruno, C. POMGnT1 mutations in congenital muscular dystrophy: genotype-phenotype correlation and expanded clinical spectrum. Arch. Neurol. 63: 1491-1495, 2006. 2. Bouchet, C., Gonzales, M., Vuillaumier-Barrot, S., Devisme, L., Lebizec, C., Alanio, E., Bazin, A., Bessieres-Grattagliano, B., Bigi, N., Blanchet, P., Bonneau, D., Bonnieres, M., and 22 others. Molecular heterogeneity in fetal forms of type II lissencephaly. Hum. Mutat. 28: 1020-1027, 2007. 3. Clement, E. M., Godfrey, C., Tan, J., Brockington, M., Torelli, S., Feng, L., Brown, S. C., Jimenez-Mallebrera, C., Sewry, C. A., Longman, C., Mein, R., Abbs, S., Vajsar, J., Schachter, H., Muntoni, F. Mild POMGnT1 mutations underlie a novel limb-girdle muscular dystrophy variant. Arch. Neurol. 65: 137-141, 2008.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
    别名
    POMGNT1 (POMGNT1 产品)
    背景
    Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 is an enzyme that in humans is encoded by the POMGNT1 gene. This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.
    分子量
    75 kDa
    基因ID
    55624
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