IDH3G 抗体 (AA 92-420)
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北京 101111
Quick Overview for IDH3G 抗体 (AA 92-420) (ABIN7602668)
抗原
See all IDH3G 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 92-420
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原理
- Anti-IDH3G Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.
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产品特性
- Anti-IDH3G Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PAIP1 recombinant protein (Position: R92-Q420). Human PAIP1 shares 97.6% amino acid (aa) sequence identity with mouse PAIP1.
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))
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别名
- IDH3G
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背景
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Background: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial is an enzyme that in humans is encoded by the IDH3G gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.
Gene Full Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
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分子量
- 40 kDa
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基因ID
- 3421
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UniProt
- P51553
抗原
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