Myotilin 抗体 (AA 9-494)
Quick Overview for Myotilin 抗体 (AA 9-494) (ABIN7602633)
抗原
See all Myotilin (MYOT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-494
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原理
- Anti-MYOT Antibody Picoband®
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产品特性
- Anti-MYOT Antibody Picoband® (ABIN7602633). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MYOT recombinant protein (Position: H9-E494). Human MYOT shares 88.9% amino acid (aa) sequence identity with mouse MYOT.
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anti-Myotilin (MYOT) (AA 259-314) antibody
MYOT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myotilin (MYOT) (AA 443-498) antibodyMYOT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myotilin (MYOT) (C-Term) antibodyMYOT 适用: 人 IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal RSO34 unconjugated
anti-Myotilin (MYOT) (AA 209-221) antibodyVerified MYOT 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Myotilin (MYOT) antibodyMYOT 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Foroud, T., Pankratz, N., Batchman, A. P., Pauciulo, M. W., Vidal, R., Miravalle, L., Goebel, H. H., Cushman, L. J., Azzarelli, B., Horak, H., Farlow, M., Nichols, W. C. A mutation in myotilin causes spheroid body myopathy. Neurology 65: 1936-1940, 2005. 2. Goebel, H. H., Muller, J., Gillen, H. W., Merritt, A. D. Autosomal dominant 'spheroid body myopathy'. Muscle Nerve 1: 14-26, 1978. 3. Hauser, M. A., Conde, C. B., Kowaljow, V., Zeppa, G., Taratuto, A. L., Torian, U. M., Vance, J., Pericak-Vance, M. A., Speer, M. C., Rosa, A. L. Myotilin mutation found in second pedigree with LGMD1A. Am. J. Hum. Genet. 71: 1428-1432, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Myotilin (MYOT)
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别名
- MYOT
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背景
- Myotilin is a protein that in humans is encoded by the MYOT gene. This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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分子量
- 55 kDa
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基因ID
- 9499
抗原
-
