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ETF1 抗体 (AA 9-342)

ETF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 3B6 unconjugated
产品编号 ABIN7602625
发货至: 中国
  • 抗原 See all ETF1 抗体
    ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 9-342
    适用
    • 13
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 10
    • 4
    小鼠
    克隆类型
    • 10
    • 4
    单克隆
    标记
    • 14
    This ETF1 antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    Anti-eRF1/ETF1 Antibody Picoband® (monoclonal, 3B6)
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-eRF1/ETF1 Antibody Picoband® (monoclonal, 3B6) (ABIN7602625). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human eRF1/ETF1 recombinant protein (Position: D9-K342).
    克隆位点
    3B6
    亚型
    IgG2a
    Top Product
    Discover our top product ETF1 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
    1. Frolova, L., Le Goff, X., Rasmussen, H. H., Cheperegin, S., Drugeon, G., Kress, M., Arman, I., Haenni, A.-L., Celis, J. E., Philippe, M., Justesen, J., Kisselev, L. A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature 372: 701-703, 1994. 2. Guenet, L., Henry, C., Toutain, B., Dubourg, C., Le Gall, J. Y., David, V., Le Treut, A. Eukaryotic translation termination factor gene (ETF1/eRF1) maps at D5S500 in a commonly deleted region of chromosome 5q31 in malignant myeloid diseases. Cytogenet. Cell Genet. 88: 82-86, 2000. 3. Hansen, L. L., Jakobsen, C. G., Justesen, J. Assignment of the human translation termination factor 1 (ETF1) to 5q31.1 and of the proximal marker D5S1995 by radiation hybrid mapping. Cytogenet. Cell Genet. 87: 256-257, 1999.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
    别名
    ETF1 (ETF1 产品)
    背景

    Synonyms: AW546468 antibody, C80305 antibody, MGC18200 antibody, MGC4569 antibody, MGC54054 antibody, OTTHUMP00000147628 antibody, OTTHUMP00000229864 antibody, OTTHUMP00000229865 antibody, OTTHUMP00000229866 antibody, OTTHUMP00000229870 antibody, OTTHUMP00000229871 antibody, OTTHUMP00000229872 antibody, Placental ribonuclease inhibitor antibody, Placental RNase inhibitor antibody, PRI antibody, RAI antibody, RI antibody, Ribonuclease inhibitor antibody, Ribonuclease/angiogenin inhibitor 1 antibody, Ribonuclease/angiogenin inhibitor antibody, RINI_HUMAN antibody, RNase inhibitor antibody, RNH 1 antibody, RNH antibody, RNH1 antibody, Rnh1 ribonuclease/angiogenin inhibitor 1 antibody

    Background: Eukaryotic translation termination factor 1 (eRF1), also known asTB3-1, is a protein that in humans is encoded by the ETF1 gene. It is mapped to 5q31.2. This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in ing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

    分子量
    49 kDa
    基因ID
    2107
    UniProt
    P62495
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