MAFA 抗体 (AA 9-308)
Quick Overview for MAFA 抗体 (AA 9-308) (ABIN7602623)
抗原
See all MAFA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-308
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原理
- Anti-MAFA Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MAFA Picoband® Antibody (ABIN7602623). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAFA recombinant protein (Position: A9-D308).
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亚型
- IgG
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anti-Transcription Factor MafA (MAFA) (AA 222-308) antibody
MAFA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Transcription Factor MafA (MAFA) antibodyMAFA 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) antibodyMAFA 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 222-308) antibodyMAFA 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 81-130) antibodyMAFA 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 300-350) antibodyMAFA 适用: 人, 小鼠, 大鼠, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 110-159) antibodyMAFA 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 71-120) antibodyMAFA 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (N-Term) antibodyMAFA 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor MafA (MAFA) (AA 203-231) antibodyMAFA 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Iacovazzo, D., Flanagan, S. E., Walker, E., Quezado, R., de Sousa Barros, F. A., Caswell, R., Johnson, M. B., Wakeling, M., Brandle, M., Guo, M., Dang, M. N., Gabrovska, P., and 14 others. MAFA missense mutation causes familial insulinomatosis and diabetes mellitus. Proc. Nat. Acad. Sci. 115: 1027-1032, 2018. 2. Olbrot, M., Rud, J., Moss, L. G., Sharma, A. Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. Proc. Nat. Acad. Sci. 99: 6737-6742, 2002. 3. Tragl, K.-H., Mayr, W. R. Familial islet-cell adenomatosis. Lancet 318: 426-428, 1977. Note: Originally Volume II. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MAFA (Transcription Factor MafA (MAFA))
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别名
- MAFA
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背景
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Synonyms: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Tissue Specificity: Preferentially expressed in regulatory T-cells (Tregs).
Background: MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. It is mapped to 8q24.3.
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分子量
- 50 kDa
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基因ID
- 389692
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途径
- Hormone Transport
抗原
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