HOXD10 抗体 (AA 9-252)
Quick Overview for HOXD10 抗体 (AA 9-252) (ABIN7602619)
抗原
See all HOXD10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-252
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原理
- Anti-HOXD10 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-HOXD10 Antibody Picoband® (ABIN7602619). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HOXD10 recombinant protein (Position: A9-K252).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dobbs, M. B., Gurnett, C. A., Pierce, B., Exner, G. U., Robarge, J., Morcuende, J. A., Cole, W. G., Templeton, P. A., Foster, B., Bowcock, A. M. HOXD10 M319K mutation in a family with isolated congenital vertical talus. J. Orthop. Res. 24: 448-453, 2006. 2. Johnson, R. L., Tabin, C. J. Molecular models for vertebrate limb development. Cell 90: 979-990, 1997. 3. Reddy, S. D. N., Ohshiro, K., Rayala, S. K., Kumar, R. MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its function. Cancer Res. 68: 8195-8200, 2008. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- HOXD10 (Homeobox D10 (HOXD10))
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别名
- HOXD10
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背景
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Synonyms: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Tissue Specificity: Preferentially expressed in regulatory T-cells (Tregs).
Background: Homeobox D10, also known as HOXD10, is a protein which in humans is encoded by the HOXD10 gene. This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
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分子量
- 40 kDa
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基因ID
- 3236
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UniProt
- P28358
抗原
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