MDH2 抗体 (AA 9-223)
Quick Overview for MDH2 抗体 (AA 9-223) (ABIN7602617)
抗原
See all MDH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 9-223
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原理
- Anti-MDH2 Antibody Picoband® (monoclonal, 5D8C1)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MDH2 Antibody Picoband® (monoclonal, 5D8C1) (ABIN7602617). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MDH2 recombinant protein (Position: A9-L223). Human MDH2 shares 97.7% and 98.1% amino acid (aa) sequence identity with mouse and rat MDH2, respectively.
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亚型
- IgG2b
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anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 25-338) antibody
MDH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) antibodyKO Validated MDH2 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (Internal Region) antibodyVerified MDH2 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 221-232) antibodyVerified MDH2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 134-246) antibodyMDH2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 86-115) antibodyMDH2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20827 unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (C-Term) antibodyMDH2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 59-338) antibodyMDH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 134-246) antibodyMDH2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2) (AA 134-246) antibodyMDH2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Ait-El-Mkadem, S., Dayem-Quere, M., Gusic, M., Chaussenot, A., Bannwarth, S., Francois, B., Genin, E. C., Fragaki, K., Volker-Touw, C. L. M., Vasnier, C., Serre, V., van Gassen, K. L. I., and 24 others. Mutations in MDH2, encoding a Krebs cycle enzyme, cause early-onset severe encephalopathy. Am. J. Hum. Genet. 100: 151-159, 2017. 2. Benn, P., Chern, C. J., Bruns, G., Craig, I. W., Croce, C. M. Assignment of the genes for human beta-glucuronidase and mitochondrial malate dehydrogenase to the region pter-q22 of chromosome 7. Cytogenet. Cell Genet. 19: 273-280, 1977. 3. Blake, N. M. Malate dehydrogenase types in the Asian-Pacific area, and a description of new phenotypes. Hum. Genet. 43: 69-80, 1978. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MDH2 (Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2))
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别名
- MDH2
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背景
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Synonyms: Cofilin-2, Cofilin, muscle isoform, CFL2
Tissue Specificity: Isoform CFL2b is expressed predominantly in skeletal muscle and heart. Isoform CFL2a is expressed in various tissues.
Background: Malate dehydrogenase, mitochondrial also known as malate dehydrogenase 2 is an enzyme that in humans is encoded by the MDH2 gene. Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 36 kDa
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基因ID
- 4191
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UniProt
- P40926
抗原
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