POMP 抗体 (AA 9-141)
Quick Overview for POMP 抗体 (AA 9-141) (ABIN7602614)
抗原
See all POMP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-141
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原理
- Anti-POMP Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-POMP Antibody Picoband® (ABIN7602614). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human POMP recombinant protein (Position: E9-L141).
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亚型
- IgG
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anti-Proteasome Maturation Protein (POMP) (AA 1-141) antibody
POMP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Maturation Protein (POMP) (AA 1-141) antibodyPOMP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Maturation Protein (POMP) antibodyPOMP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Maturation Protein (POMP) (AA 1-141) antibodyPOMP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome Maturation Protein (POMP) (AA 1-141) antibodyPOMP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Maturation Protein (POMP) (AA 105-131), (C-Term) antibodyPOMP 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43046 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Brehm, A., Liu, Y., Sheikh, A., Marrero, B., Omoyinmi, E., Zhou, Q., Montealegre, G., Biancotto, A., Reinhardt, A., Almeida de Jesus, A., Pelletier, M., Tsai, W. L., and 31 others. Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production. J. Clin. Invest. 125: 4196-4211, 2015. Note: Erratum: J. Clin. Invest. 126: 795 only, 2016. 2. Chondrogianni, N., Gonos, E. S. Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence. Exp. Gerontol. 42: 899-903, 2007. 3. Dahlqvist, J., Klar, J., Tiwari, N., Schuster, J., Torma, H., Badhai, J., Pujol, R., van Steensel, M. A. M., Brinkhuizen, T., Gijezen, L., Chaves, A., Tadini, G., Vahlquist, A., Dahl, N. A single-nucleotide deletion in the POMP 5-prime UTR causes a transcriptional switch and altered epidermal proteasome distribution in KLICK genodermatosis. Am. J. Hum. Genet. 86: 596-603, 2010. Note: Erratum: Am. J. Hum. Genet. 86: 655 only, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- POMP (Proteasome Maturation Protein (POMP))
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别名
- POMP
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背景
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Synonyms: NACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2, NLRP2, NALP2, NBS1, PAN1, PYPAF2
Tissue Specificity: Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.
Background: Proteasome maturation protein is a protein that in humans is encoded by the POMP gene. The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
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分子量
- 16 kDa
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基因ID
- 51371
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UniProt
- Q9Y244
抗原
-
