SERPINC1 抗体 (AA 89-464)
Quick Overview for SERPINC1 抗体 (AA 89-464) (ABIN7602610)
抗原
See all SERPINC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 89-464
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原理
 - Anti-Antithrombin III/SERPINC1 Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-Antithrombin III/SERPINC1 Antibody Picoband® (ABIN7602610). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived human Antithrombin III/SERPINC1 recombinant protein (Position: R89-K464).
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Baud, O., Picard, V., Durand, P., Duchemin, J., Proulle, V., Albenc-Gelas, M., Devictor, D., Dreyfus, M. Intracerebral hemorrhage associated with a novel antithrombin gene mutation in a neonate. J. Pediat. 139: 741-743, 2001. 2. Fischer, A. M., Cornu, P., Sternberg, C., Meriane, F., Dautzenberg, M. D., Chafa, O., Beguin, S., Desnos, M. Antithrombin III Alger: a new homozygous AT III variant. Thromb. Haemost. 55: 218-221, 1986. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
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别名
 - SERPINC1
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背景
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Synonyms: Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL,
Tissue Specificity: Widespread, most predominant in spleen, lung and prostate.
Background: Serpin peptidase inhibitor, clade C(antithrombin), member 1, also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
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分子量
 - 53 kDa
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基因ID
 - 462
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UniProt
 - P01008
 
抗原
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