PC 抗体 (AA 88-1165)
Our Local Distributor
北京 101111
Quick Overview for PC 抗体 (AA 88-1165) (ABIN7602587)
抗原
See all PC 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 88-1165
-
原理
- Anti-Pyruvate Carboxylase/PC Antibody
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
预测反应
- Human PC shares 97%,96.6% amino acid (aa) sequence identity with mouse,rat PC,respectively.
-
产品特性
- Anti-Pyruvate Carboxylase/PC Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Pyruvate Carboxylase/PC recombinant protein (Position: R88-D1165). Human PC shares 97% and 96.6% amino acid (aa) sequence identity with mouse and rat PC, respectively.
-
亚型
- IgG
-
-
anti-Pyruvate Carboxylase (PC) (AA 36-486) antibody
PC 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (Internal Region) antibodyVerified PC 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (AA 357-406) antibodyPC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Carboxylase (PC) (AA 981-1030) antibodyPC 适用: 人, 小鼠, Pig, 犬, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
-
-
- PC (Pyruvate Carboxylase (PC))
-
别名
- Pyruvate Carboxylase
-
背景
-
Background: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
Gene Full Name: pyruvate carboxylase
-
分子量
- 125 kDa
-
基因ID
- 5091
-
UniProt
- P11498
抗原
-
