ERLIN2 抗体 (AA 87-339)
Quick Overview for ERLIN2 抗体 (AA 87-339) (ABIN7602582)
抗原
See all ERLIN2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 87-339
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原理
- Anti-Erlin-2/ERLIN2 Antibody Picoband® (monoclonal, 3H9A2)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Erlin-2/ERLIN2 Antibody Picoband® (monoclonal, 3H9A2) (ABIN7602582). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Erlin-2/ERLIN2 recombinant protein (Position: D87-N339).
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亚型
- IgG2b
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anti-ER Lipid Raft Associated 2 (ERLIN2) (AA 47-339) antibody
ERLIN2 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (AA 212-339) antibodyERLIN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (AA 47-339) antibodyERLIN2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) antibodyERLIN2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (AA 307-333), (C-Term) antibodyERLIN2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB38591 unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (AA 212-339) antibodyERLIN2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (AA 25-206) antibodyERLIN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (C-Term) antibodyVerified ERLIN2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (C-Term) antibodyERLIN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ER Lipid Raft Associated 2 (ERLIN2) (Middle Region) antibodyERLIN2 适用: 人, 大鼠, 小鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Al-Saif, A., Bohlega, S., Al-Mohanna, F. Loss of ERLIN2 function leads to juvenile primary lateral sclerosis. Ann. Neurol. 72: 510-516, 2012. 2. Alazami, A. M., Adly, N., Al Dhalaan, H., Alkuraya, F. S. A nullimorphic ERLIN2 mutation defines a complicated hereditary spastic paraplegia locus (SPG18). Neurogenetics 12: 333-336, 2011. 3. Browman, D. T., Resek, M. E., Zajchowski, L. D., Robbins, S. M. Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER. J. Cell Sci. 119: 3149-3160, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))
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别名
- ERLIN2
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背景
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Synonyms: T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, hTRiC5, CCT3, CCTG, TRIC5
Tissue Specificity: Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Background: Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene. This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 43 kDa
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基因ID
- 11160
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UniProt
- O94905
抗原
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