BSCL2 抗体 (AA 87-231)
Quick Overview for BSCL2 抗体 (AA 87-231) (ABIN7602581)
抗原
See all BSCL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 87-231
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原理
- Anti-BSCL2/Seipin Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-BSCL2/Seipin Antibody Picoband® (ABIN7602581). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BSCL2/Seipin recombinant protein (Position: A87-P231).
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亚型
- IgG
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anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 263-354) antibody
BSCL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 1-400) antibodyBSCL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 50-150) antibodyBSCL2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 259-357) antibodyBSCL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 259-357) antibodyBSCL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 362-410) antibodyBSCL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (C-Term) antibodyBSCL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 78-107), (N-Term) antibodyBSCL2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB19045 unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (C-Term) antibodyBSCL2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) (AA 85-115), (N-Term) antibodyBSCL2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Agarwal, A. K., Garg, A. Seipin: a mysterious protein. Trends Molec. Med. 10: 440-444, 2004. 2. Auer-Grumbach, M., Loscher, W. N., Wagner, K., Petek, E., Korner, E., Offenbacher, H., Hartung, H.-P. Phenotypic and genotypic heterogeneity in hereditary motor neuronopathy type V: a clinical, electrophysiological and genetic study. Brain 123: 1612-1623, 2000. 3. Auer-Grumbach, M., Schlotter-Weigel, B., Lochmuller, H., Strobl-Wildemann, G., Auer-Grumbach, P., Fischer, R., Offenbacher, H., Zwick, E. B., Robl, T., Hartl, G., Hartung, H.-P., Wagner, K., Windpassinger, C., Austrian Peripheral Neuropathy Study Group. Phenotypes of the N88S Berardinelli-Seip congenital lipodystrophy 2 mutation. Ann. Neurol. 57: 415-424, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))
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别名
- BSCL2
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背景
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Synonyms: Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1, NAP-2
Background: Seipin is a protein that in humans is encoded by the BSCL2 gene. This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
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分子量
- 46 kDa
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基因ID
- 26580
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UniProt
- Q96G97
抗原
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