PYHIN1 抗体 (AA 86-488)
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北京 101111
Quick Overview for PYHIN1 抗体 (AA 86-488) (ABIN7602574)
抗原
See all PYHIN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 86-488
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原理
- Anti-PYHIN1 Antibody
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产品特性
- Anti-PYHIN1 Antibody (ABIN7602574). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PYHIN1 recombinant protein (Position: K86-H488). Human PYHIN1 shares 45.6% amino acid (aa) sequence identity with mouse PYHIN1.
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亚型
- IgG
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anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 26-55), (N-Term) antibody
PYHIN1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26421 unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 1-245) antibodyPYHIN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (AA 38-87) antibodyPYHIN1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyrin and HIN Domain Family, Member 1 (PYHIN1) (N-Term) antibodyPYHIN1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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别名
- PYHIN1
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背景
- The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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分子量
- 55 kDa
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基因ID
- 149628
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UniProt
- Q6K0P9
抗原
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