ALDOB 抗体 (AA 85-364)
Quick Overview for ALDOB 抗体 (AA 85-364) (ABIN7602563)
抗原
See all ALDOB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 85-364
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原理
- Anti-Aldolase/ALDOB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Aldolase/ALDOB Antibody Picoband® (ABIN7602563). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Aldolase/ALDOB recombinant protein (Position: Y85-Y364).
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亚型
- IgG
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anti-Aldolase B, Fructose-Bisphosphate (ALDOB) antibody
ALDOB 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) antibodyALDOB 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (AA 1-200) antibodyALDOB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (N-Term) antibodyALDOB 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, 豚鼠, 马, 绵羊, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (AA 88-170) antibodyALDOB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (AA 1-364) antibodyALDOB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) antibodyALDOB 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (AA 108-157) antibodyALDOB 适用: 人, 大鼠, 小鼠, Pig, 兔, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (N-Term) antibodyALDOB 适用: 人, 大鼠, 小鼠, Pig, Cow, 兔, 犬, 豚鼠, 马, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aldolase B, Fructose-Bisphosphate (ALDOB) (AA 1-364) antibodyALDOB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Monkey, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dalby AR, Tolan DR, Littlechild JA (November 2001). "The structure of human liver fructose-1,6-bisphosphate aldolase". Acta Crystallogr. D. 57 (Pt 11): 1526-33. 2. Henry I, Gallano P, Besmond C, Weil D, Mattei MG, Turleau C, Boué J, Kahn A, Junien C (July 1985). "The structural gene for aldolase B (ALDB) maps to 9q13----32". Ann. Hum. Genet. 49 (Pt 3): 173-80. 3. Sygusch J, Beaudry D, Allaire M (November 1987). "Molecular architecture of rabbit skeletal muscle aldolase at 2.7-A resolution". Proc. Natl. Acad. Sci. U.S.A. 84 (22): 7846-50. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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别名
- ALDOB
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背景
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Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Tissue Specificity: Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.
Background: Aldolase B also known as fructose-bisphosphate aldolase B or liver-type aldolase is one of three isoenzymes (A, B, and C) of the class I fructose 1,6-bisphosphate aldolase enzyme (EC 4.1.2.13), and plays a key role in both glycolysis and gluconeogenesis. It is mapped to 9q31.1. Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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分子量
- 39 kDa
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基因ID
- 229
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UniProt
- P05062
抗原
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