IRS2 抗体 (AA 83-1338)
Quick Overview for IRS2 抗体 (AA 83-1338) (ABIN7602540)
抗原
See all IRS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-1338
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原理
- Anti-IRS2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IRS2 Antibody Picoband® (ABIN7602540). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IRS2 recombinant protein (Position: R83-E1338).
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亚型
- IgG
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anti-Insulin Receptor Substrate 2 (IRS2) (AA 501-600) antibody
IRS2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 766-1001) antibodyIRS2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 510-650) antibodyIRS2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 1309-1338), (C-Term) antibodyIRS2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15641 unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (C-Term) antibodyIRS2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 985-1255) antibodyIRS2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 660-700) antibodyIRS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 1288-1338) antibodyIRS2 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (C-Term) antibodyIRS2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Sun, X. J., Wang, L.-M., Zhang, Y., Yenush, L., Myers, M. G., Jr., Glasheen, E., Lane, W. S., Pierce, J. H., White, M. F. Role of IRS-2 in insulin and cytokine signalling. Nature 377: 173-177, 1995. 2. Ogihara T, Isobe T, Ichimura T, Taoka M, Funaki M, Sakoda H, Onishi Y, Inukai K, Anai M, Fukushima Y, Kikuchi M, Yazaki Y, Oka Y, Asano T (Oct 1997). "14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain". J Biol Chem 272 (40): 25267-74. 3. "Entrez Gene: IRS2 insulin receptor substrate 2" -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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别名
- IRS2
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背景
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Synonyms: Oncostatin-M, OSM, Osm
Tissue Specificity: Widely expressed. Expressed at higher levels in liver, skin and spleen.
Background: Insulin receptor substrate 2 (IRS2) is a protein that in humans is encoded by the IRS2 gene. It is mapped to 13q34. This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. IRS2 is expressed in many cells, it may be essential for signaling by several receptor systems.
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分子量
- 180 kDa
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基因ID
- 8660
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UniProt
- Q9Y4H2
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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