EIF3C 抗体 (AA 81-637)
Quick Overview for EIF3C 抗体 (AA 81-637) (ABIN7602528)
抗原
See all EIF3C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-637
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原理
- Anti-EIF3C Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-EIF3C Antibody Picoband® (ABIN7602528). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EIF3C recombinant protein (Position: E81-Q637).
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) (AA 694-913) antibody
EIF3C 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) antibodyEIF3C 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) (AA 201-500) antibodyEIF3C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) antibodyEIF3C 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) (AA 126-155), (N-Term) antibodyEIF3C 适用: 人 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) (C-Term) antibodyEIF3C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C) antibodyEIF3C 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Asano, K., Kinzy, T. G., Merrick, W. C., Hershey, J. W. B. Conservation and diversity of eukaryotic translation initiation factor eIF3. J. Biol. Chem. 272: 1101-1109, 1997. 2. Gross, M. B. Personal Communication. Baltimore, Md. 5/20/2011. 3. Scoles, D. R., Yong, W. H., Qin, Y., Wawrowsky, K., Pulst, S. M. Schwannomin inhibits tumorigenesis through interaction with the eukaryotic initiation factor subunit c (elF3c). Hum. Molec. Genet. 15: 1059-1070, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
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别名
- EIF3C
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背景
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Synonyms: Mediator of RNA polymerase II transcription subunit 4, Activator-recruited cofactor 36 kDa component, ARC36, Mediator complex subunit 4, TRAP/SMCC/PC2 subunit p36 subunit, Vitamin D3 receptor-interacting protein complex 36 kDa component, DRIP36, MED4, ARC36, DRIP36, VDRIP, HSPC126
Background: Eukaryotic translation initiation factor 3 subunit C (eIF3c) is a protein that in humans is encoded by the EIF3C gene. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
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分子量
- 105 kDa
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基因ID
- 8663
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UniProt
- Q99613
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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