SIRT5 抗体 (AA 81-310)
Quick Overview for SIRT5 抗体 (AA 81-310) (ABIN7602524)
抗原
See all SIRT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-310
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原理
- Anti-SIRT5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SIRT5 Antibody Picoband® (ABIN7602524). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SIRT5 recombinant protein (Position: D81-S310).
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亚型
- IgG
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anti-Sirtuin 5 (SIRT5) (AA 37-310) antibody
SIRT5 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) antibodySIRT5 适用: 人, 大鼠 WB, IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Sirtuin 5 (SIRT5) (AA 120-170) antibodySIRT5 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 179-228) antibodySIRT5 适用: 人, 小鼠, Cow, 山羊, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (C-Term) antibodySIRT5 适用: 人, 山羊, Pig, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (Middle Region) antibodySIRT5 适用: 人, 小鼠, Cow, 山羊, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 37-310) antibodySIRT5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 60-212) antibodySIRT5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 184-233) antibodySIRT5 适用: 人, 小鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sirtuin 5 (SIRT5) (AA 1-310) antibodySIRT5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Du, J., Zhou, Y., Su, X., Yu, J. J., Khan, S., Jiang, H., Kim, J., Woo, J., Kim, J. H., Choi, B. H., He, B., Chen, W., Zhang, S., Cerione, R. A., Auwerx, J., Hao, Q., Lin, H. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science 334: 806-809, 2011. 2. Frye, R. A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 260: 273-279, 1999. 3. Lombard, D. B., Alt, F. W., Cheng, H.-L., Bunkenborg, J., Streeper, R. S., Mostoslavsky, R., Kim, J., Yancopoulos, G., Valenzuela, D., Murphy, A., Yang, Y., Chen, Y., Hirschey, M. D., Bronson, R. T., Haigis, M., Guarente, L. P., Farese, R. V., Jr., Weissman, S., Verdin, E., Schwer, B. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Molec. Cell. Biol. 27: 8807-8814, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SIRT5 (Sirtuin 5 (SIRT5))
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别名
- SIRT5
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背景
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Synonyms: Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12, CASP2, ICH1, NEDD2
Tissue Specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Background: Sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), also known as SIRT5 is a protein which in humans in encoded by the SIRT5 gene and in other species by the orthologous Sirt5 gene. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
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分子量
- 34 kDa
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基因ID
- 23408
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途径
- SARS-CoV-2 Protein Interactome
抗原
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