ALKBH5 抗体 (AA 81-180)
Quick Overview for ALKBH5 抗体 (AA 81-180) (ABIN7602521)
抗原
See all ALKBH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-180
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原理
- Anti-ALKBH5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ALKBH5 Antibody Picoband® (ABIN7602521). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ALKBH5 recombinant protein (Position: E81-R180).
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 245-394) antibody
ALKBH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 302-330) antibodyALKBH5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB38474 unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 1-458) antibodyALKBH5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (Internal Region) antibodyALKBH5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/12/2010. 2. Tsujikawa, K., Koike, K., Kitae, K., Shinkawa, A., Arima, H., Suzuki, T., Tsuchiya, M., Makino, Y., Furukawa, T., Konishi, N., Yamamoto, H. Expression and sub-cellular localization of human ABH family molecules. J. Cell. Molec. Med. 11: 1105-1116, 2007. 3. Zheng, G., Dahl, J. A., Niu, Y., Fedorcsak, P., Huang, C.-M., Li, C. J., Vagbo, C. B., Shi, Y., Wang, W.-L., Song, S.-H., Lu, Z., Bosmans, R. P. G., and 16 others. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Molec. Cell 49: 18-29, 2013. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
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别名
- ALKBH5
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背景
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Synonyms: RNA demethylase ALKBH5, Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5, ALKBH5, ABH5, OFOXD1
Tissue Specificity: Widely expressed, with highest expression in lung, followed by testis, pancreas, spleen and ovary.
Background: RNA demethylase ALKBH5 is an enzyme that in humans is encoded by the ALKBH5 gene. It is mapped to 17p11.2. N (6)-methyladenosine (m (6)A) is the most prevalent modification of mRNA. ALKBH5 functions as a demethylase that removes m (6)A from mRNAs.
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分子量
- 52 kDa
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基因ID
- 54890
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UniProt
- Q6P6C2
抗原
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