TTI2 抗体 (AA 80-508)
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- 抗原 See all TTI2 抗体
- TTI2 (TELO2 Interacting Protein 2 (TTI2))
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抗原表位
- AA 80-508
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTI2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- Anti-TTI2 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-TTI2 Antibody Picoband® (ABIN7602516). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human TTI2 recombinant protein (Position: E80-T508).
- 亚型
- IgG
- Top Product
- Discover our top product TTI2 Primary Antibody
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anti-TELO2 Interacting Protein 2 (TTI2) (AA 159-264) antibody
TTI2 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-TELO2 Interacting Protein 2 (TTI2) (N-Term) antibodyTTI2 适用: 人, Cow, 犬, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/11/2012. 2. Hurov, K. E., Cotta-Ramusino, C., Elledge, S. J. A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. Genes Dev. 24: 1939-1950, 2010. 3. Langouet, M., Saadi, A., Rieunier, G., Moutton, S., Siquier-Pernet, K., Fernet, M., Nitschke, P., Munnich, A., Stern, M.-H., Chaouch, M., Colleaux, L. Mutation in TTI2 reveals a role for triple T complex in human brain development. Hum. Mutat. 34: 1472-1476, 2013. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- TTI2 (TELO2 Interacting Protein 2 (TTI2))
- 别名
- TTI2 (TTI2 产品)
- 背景
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Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8, CPAMD8, KIAA1283
Tissue Specificity: Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body.
Background: TELO2 interacting protein 2 is a protein that in humans is encoded by the TTI2 gene. This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance.
- 分子量
- 60 kDa
- 基因ID
- 80185
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