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NLRP2 抗体 (AA 80-1044)

Name: NLRP2 抗体 (AA 80-1044)
SKU: ABIN7602506
Availability: OutOfStock

This anti-NLRP2 antibody is a 兔多克隆 antibody detecting NLRP2 in WB, ELISA, IF, IP, ICC 和 FACS. Suitable for 人.

产品编号 ABIN7602506

发货至: 中国

Quick Overview for NLRP2 抗体 (AA 80-1044) (ABIN7602506)

抗原

See all NLRP2 抗体

NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This NLRP2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Discover our top product NLRP2 Primary Antibody

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AA 80-1044

原理

Anti-NLRP2 Antibody Picoband®

产品特性

Anti-NLRP2 Antibody Picoband® (ABIN7602506). Tested in WB, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human NLRP2 recombinant protein (Position: H80-D1044).
anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-1062) antibody
NLRP2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-220) antibody
NLRP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (C-Term) antibody
NLRP2 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-220) antibody
NLRP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (C-Term) antibody
Verified NLRP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-846) antibody
NLRP2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B10 unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 1-1062) antibody
NLRP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 150-200) antibody
NLRP2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) antibody
NLRP2 适用: 人, 小鼠, Hamster, 猴 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-NLR Family, Pyrin Domain Containing 2 (NLRP2) (AA 620-700) antibody
NLRP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., Tschopp, J. NALP3 forms an IL-1-beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20: 319-325, 2004. 2. Bruey, J. M., Bruey-Sedano, N., Newman, R., Chandler, S., Stehlik, C., Reed, J. C. PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappa-B and caspase-1 activation in macrophages. J. Biol. Chem. 279: 51897-51907, 2004. 3. Kuchmiy, A. A., D'Hont, J., Hochepied, T., Lamkanfi, M. NLRP2 controls age-associated maternal fertility. J. Exp. Med. 213: 2851-2860, 2016.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

别名

NLRP2

背景

NACHT, LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene. This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.

分子量

121 kDa

基因ID

55655

途径

Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome