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TTLL12 抗体 (AA 8-634)

TTLL12 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7602497
发货至: 中国
  • 抗原 See all TTLL12 products
    TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))
    抗原表位
    • 1
    • 1
    AA 8-634
    适用
    • 8
    • 3
    • 2
    • 1
    • 1
    宿主
    • 5
    • 3
    克隆类型
    • 5
    • 3
    多克隆
    标记
    • 8
    This TTLL12 antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 4
    • 4
    • 3
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA
    原理
    Anti-TTLL12 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-TTLL12 Antibody Picoband® (ABIN7602497). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human TTLL12 recombinant protein (Position: E8-Q634).
    亚型
    IgG
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Brants, J., Semenchenko, K., Wasylyk, C., Robert, A., Carles, A., Zambrano, A., Pradeau-Aubreton, K., Birck, C., Schalken, J. A., Poch, O., de Mey, J., Wasylyk, B. Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis. PLoS One 7: e51258, 2012. 2. Gross, M. B. Personal Communication. Baltimore, Md. 6/28/2021. 3. Ju, L.-G., Zhu, Y., Lei, P.-J., Yan, D., Zhu, K., Wang, X., Li, Q.-L., Li, X.-J., Chen, J.-W., Li, L.-Y., Wu, M. TTLL12 inhibits the activation of cellular antiviral signaling through interaction with VISA/MAVS. J. Immun. 198: 1274-1284, 2017.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原
    TTLL12 (Tubulin tyrosine Ligase-Like Family, Member 12 (TTLL12))
    别名
    TTLL12 (TTLL12 产品)
    背景

    Synonyms: DAP3-binding cell death enhancer 1, Death ligand signal enhancer, DELE1, DELE, KIAA0141

    Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

    Background: Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm.

    分子量
    75 kDa
    基因ID
    23170
    UniProt
    Q14166
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