FLCN 抗体 (AA 8-551)
Quick Overview for FLCN 抗体 (AA 8-551) (ABIN7602491)
抗原
See all FLCN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-551
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原理
- Anti-FLCN Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FLCN Picoband® Antibody (ABIN7602491). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FLCN recombinant protein (Position: C8-K551).
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亚型
- IgG
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anti-Folliculin (FLCN) (AA 1-130) antibody
FLCN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Folliculin (FLCN) antibodyFLCN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Folliculin (FLCN) (AA 291-579) antibodyFLCN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Folliculin (FLCN) antibodyFLCN 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Folliculin (FLCN) (AA 1-342) antibodyFLCN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Folliculin (FLCN) (AA 505-534), (C-Term) antibodyFLCN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20960 unconjugated
anti-Folliculin (FLCN) (AA 198-296) antibodyFLCN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Folliculin (FLCN) (AA 506-555) antibodyFLCN 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Folliculin (FLCN) (AA 48-97) antibodyFLCN 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Folliculin (FLCN) (AA 1-342) antibodyFLCN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Painter, J. N., Tapanainen, H., Somer, M., Tukiainen, P., Aittomaki, K. A 4-bp deletion in the Birt-Hogg-Dube gene (FLCN) causes dominantly inherited spontaneous pneumothorax. Am. J. Hum. Genet. 76: 522-527, 2005. 2. Ren, H.-Z., Zhu, C.-C., Yang, C., Chen, S.-L., Xie, J., Hou, Y.-Y., Xu, Z.-F., Wang, D.-J., Mu, D.-K., Ma, D.-H., Wang, Y., Ye, M.-H., Ye, Z.-R., Chen, B.-F., Wang, C.-G., Lin, J., Qiao, D., Yi, L. Mutation analysis of the FLCN gene in Chinese patients with sporadic and familial isolated primary spontaneous pneumothorax. Clin. Genet. 74: 178-183, 2008. 3. Schmidt, L. S., Nickerson, M. L., Warren, M. B., Glenn, G. M., Toro, J. R., Merino, M. J., Turner, M. L., Choyke, P. L., Sharma, N., Peterson, J., Morrison, P., Maher, E. R., Walther, M. M., Zbar, B., Linehan, W. M. Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dube syndrome. Am. J. Hum. Genet. 76: 1023-1033, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FLCN (Folliculin (FLCN))
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别名
- FLCN
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物质类
- Amino Acid
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背景
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Synonyms: Folliculin, BHD skin lesion fibrofolliculoma protein, Birt-Hogg-Dube syndrome protein, FLCN, BHD
Tissue Specificity: Skeletal muscle, heart, colon, testis, ovary and pancreas.
Background: Folliculin also known as FLCN, Birt-Hogg-Dubé syndrome protein or FLCN_HUMAN is a protein that in humans is associated with Birt-Hogg-Dubé syndrome and hereditary spontaneous pneumothorax. It is encoded by the Folliculin (FLCN) gene (alias BHD, FLCL) that acts as a tumor suppressor gene. It is mapped to 17p11.2. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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分子量
- 70 kDa
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基因ID
- 201163
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途径
- Cell-Cell Junction Organization
抗原
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