SORD 抗体 (AA 8-357)
Quick Overview for SORD 抗体 (AA 8-357) (ABIN7602486)
抗原
See all SORD 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 8-357
-
原理
- Anti-Sorbitol Dehydrogenase/SORD Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Sorbitol Dehydrogenase/SORD Antibody Picoband® (ABIN7602486). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Sorbitol Dehydrogenase/SORD recombinant protein (Position: N8-P357).
-
亚型
- IgG
-
-
anti-Sorbitol Dehydrogenase (SORD) (AA 1-110) antibody
SORD 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D3 unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 1-357) antibodySORD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 98-355) antibodySORD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 2-357) antibodySORD 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 4-344) antibodySORD 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (C-Term) antibodyVerified SORD 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 1-357) antibodySORD 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 1-357) antibodySORD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Sorbitol Dehydrogenase (SORD) (AA 201-357) antibodySORD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sorbitol Dehydrogenase (SORD) (Internal Region) antibodySORD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Carr, I. M., Markham, A. F., Coletta, P. L. Identification and characterisation of a sequence related to human sorbitol dehydrogenase. Europ. J. Biochem. 245: 760-767, 1997. 2. Carr, I. M., Markham, A. F. Molecular genetic analysis of the human sorbitol dehydrogenase gene. Mammalian Genome 6: 645-652, 1995. 3. Carr, I. M., Whitehouse, A., Coletta, P. L., Markham, A. F. Structural and evolutionary characterization of the human sorbitol dehydrogenase gene duplication. Mammalian Genome 9: 1042-1048, 1998. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- SORD (Sorbitol Dehydrogenase (SORD))
-
别名
- SORD
-
背景
-
Synonyms: Fascin-2, Retinal fascin, FSCN2
Tissue Specificity: Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.
Background: Sorbitol dehydrogenase is an enzyme that in humans is encoded by the SORD gene. Sorbitol dehydrogenase (SORD) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.
-
分子量
- 43 kDa
-
基因ID
- 6652
-
UniProt
- Q00796
抗原
-
