SETD1A 抗体 (AA 8-153)
Quick Overview for SETD1A 抗体 (AA 8-153) (ABIN7602469)
抗原
See all SETD1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 8-153
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原理
- Anti-SET1/SETD1A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SET1/SETD1A Antibody Picoband® (ABIN7602469). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SET1/SETD1A recombinant protein (Position: D8-K153).
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亚型
- IgG
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anti-SET Domain Containing 1A (SETD1A) antibody
SETD1A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 1A (SETD1A) (AA 188-304) antibodySETD1A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 1A (SETD1A) (AA 927-956) antibodySETD1A 适用: 人 WB 宿主: 兔 Polyclonal RB41018 unconjugated
anti-SET Domain Containing 1A (SETD1A) (Internal Region), (N-Term) antibodySETD1A 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Guipponi, M., Santoni, F. A., Setola, V., Gehrig, C., Rotharmel, M., Cuenca, M., Guillin, O., Dikeos, D., Georgantopoulos, G., Papadimitrou, G., Curtis, L., Meary, A., and 9 others. Exome sequencing in 53 sporadic cases of schizophrenia identified 18 putative candidate genes. PLoS One 9: e112745, 2014. Note: Electronic Article. Erratum: PLoS One: 10: e0141630, 2015. 2. Lee, J.-H., Skalnik, D. G. CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J. Biol. Chem. 280: 41725-41731, 2005. 3. Li, Y., Han, J., Zhang, Y., Cao, F., Liu, Z., Li, S., Wu, J., Hu, C., Wang, Y., Shuai, J., Chen, J., Cao, L., Li, D., Shi, P., Tian, C., Zhang, J., Dou, Y., Li, G., Chen, Y., Lei, M. Structural basis for activity regulation of MLL family methyltransferases. Nature 530: 447-452, 2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SETD1A (SET Domain Containing 1A (SETD1A))
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别名
- SETD1A
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背景
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Synonyms: Histone-lysine N-methyltransferase SETD1A, Lysine N-methyltransferase 2F, SET domain-containing protein 1A, Hset1a, Set1/Ash2 histone methyltransferase complex subunit SET1, SETD1A, KIAA0339, KMT2F, SET1, SET1A
Background: Histone-lysine N-methyltransferase SETD1A is an enzyme that in humans is encoded by the SETD1A gene. It is mapped to 16p11.2. The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.
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分子量
- 186 kDa
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基因ID
- 9739
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UniProt
- O15047
抗原
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