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BRDT 抗体 (AA 795-947)

This anti-BRDT antibody is a 兔 多克隆 antibody detecting BRDT in WB, ELISA 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602468
发货至: 中国

Quick Overview for BRDT 抗体 (AA 795-947) (ABIN7602468)

抗原

See all BRDT 抗体
BRDT (Bromodomain, Testis-Specific (BRDT))

适用

  • 16
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  • 1
人, 小鼠, 大鼠

宿主

  • 14
  • 1
  • 1

克隆类型

  • 16
多克隆

标记

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This BRDT antibody is un-conjugated

应用范围

  • 13
  • 9
  • 2
  • 2
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 2
    • 2
    • 1
    AA 795-947

    原理

    Anti-BRDT Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-BRDT Antibody Picoband® (ABIN7602468). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human BRDT recombinant protein (Position: Q795-D947).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Gaucher, J., Boussouar, F., Montellier, E., Curtet, S., Buchou, T., Bertrand, S., Hery, P., Jounier, S., Depaux, A., Vitte, A.-L., Guardiola, P., Pernet, K., Debernardi, A., Lopez, F., Holota, H., Imbert, J., Wolgemuth, D. J., Gerard, M., Rousseaux, S., Khochbin, S. Bromodomain-dependent stage-specific male genome programming by Brdt. EMBO J. 31: 3809-3820, 2012. 2. Jones, M. H., Numata, M., Shimane, M. Identification and characterization of BRDT: a testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh. Genomics 45: 529-534, 1997. 3. Li, L., Sha, Y., Wang, X., Li, P., Wang, J., Kee, K., Wang, B. Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa. Oncotarget 8: 19914-19922, 2017.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    BRDT (Bromodomain, Testis-Specific (BRDT))

    别名

    BRDT

    背景

    Synonyms: Transmembrane protein 107,TMEM107,DC20, UNQ638/PRO1268,

    Tissue Specificity: Ubiquitous. .

    Background: Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene. BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene.

    分子量

    180 kDa

    基因ID

    676

    UniProt

    Q58F21
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