Factor XI 抗体 (AA 79-155)
Quick Overview for Factor XI 抗体 (AA 79-155) (ABIN7602456)
抗原
See all Factor XI (F11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 79-155
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原理
- Anti-FXI/F11 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FXI/F11 Antibody Picoband® (ABIN7602456). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FXI/F11 recombinant protein (Position: K79-Q155).
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亚型
- IgG
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anti-Coagulation Factor XI (F11) (AA 286-385) antibody
F11 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Coagulation Factor XI (F11) (AA 1-625) antibodyF11 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) (AA 170-398) antibodyF11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) (AA 275-516) antibodyF11 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) antibodyF11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) (AA 157-389) antibodyF11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) (AA 19-387) antibodyF11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) (AA 1-625) antibodyF11 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Coagulation Factor XI (F11) (AA 281-307) antibodyF11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19294 unconjugated
anti-Coagulation Factor XI (F11) (AA 288-315), (Middle Region) antibodyF11 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Asakai, R., Chung, D. W., Davie, E. W., Seligsohn, U. Factor XI deficiency in Ashkenazi Jews in Israel. New Eng. J. Med. 325: 153-158, 1991. 2. Asakai, R., Chung, D. W., Ratnoff, O. D., Davie, E. W. Factor XI (plasma thromboplastin antecedent) deficiency in Ashkenazi Jews is a bleeding disorder that can result from three types of point mutations. Proc. Nat. Acad. Sci. 86: 7667-7671, 1989. 3. Asakai, R., Davie, E. W., Chung, D. W. Organization of the gene for human factor XI. Biochemistry 26: 7221-7228, 1987. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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别名
- F11
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背景
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Synonyms: Purine nucleoside phosphorylase,PNP,2.4.2.1,Inosine phosphorylase,Inosine-guanosine phosphorylase,PNP,NP,
Tissue Specificity: Expressed in red blood cells, overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. .
Background: Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene. This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
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分子量
- 150 kDa
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基因ID
- 2160
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UniProt
- P03951
抗原
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