PIK3AP1 抗体 (AA 78-583)
Quick Overview for PIK3AP1 抗体 (AA 78-583) (ABIN7602451)
抗原
See all PIK3AP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 78-583
-
原理
- Anti-PIK3AP1 Antibody Picoband®
-
交叉反应 （详细）
- No cross reactivity with other proteins.
-
产品特性
- Anti-PIK3AP1 Antibody Picoband® (ABIN7602451). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PIK3AP1 recombinant protein (Position: H78-R583). Human PIK3AP1 shares 83.8% amino acid (aa) sequence identity with mouse PIK3AP1.
-
亚型
- IgG
-
-
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) antibody
PIK3AP1 适用: 人, 大鼠, 猴 WB, FACS 宿主: 小鼠 Monoclonal 6H6 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) antibodyPIK3AP1 适用: 人, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 7G9 unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 489-730) antibodyPIK3AP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 397-650) antibodyPIK3AP1 适用: 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 293-404) antibodyPIK3AP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) (AA 601-700) antibodyPIK3AP1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C2 unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Okada, T., Maeda, A., Iwamatsu, A., Gotoh, K., Kurosaki, T. BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. Immunity 13: 817-827, 2000. 2. Yamazaki, T., Kurosaki, T. Contribution of BCAP to maintenance of mature B cells through c-Rel. Nature Immun. 4: 780-786, 2003. 3. Yamazaki, T., Takeda, K., Gotoh, K., Takeshima, H., Akira, S., Kurosaki, T. Essential immunoregulatory role for BCAP in B cell development and function. J. Exp. Med. 195: 535-545, 2002. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))
-
别名
- PIK3AP1
-
背景
-
Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K)), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.
-
分子量
- 90 kDa
-
基因ID
- 118788
-
途径
- Activation of Innate immune Response, BCR Signaling, Warburg Effect
抗原
-
