TRIM2 抗体 (AA 78-398)
Quick Overview for TRIM2 抗体 (AA 78-398) (ABIN7602449)
抗原
See all TRIM2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 78-398
-
原理
- Anti-TRIM2 Antibody Picoband®
-
产品特性
- Anti-TRIM2 Antibody Picoband® (ABIN7602449). Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human TRIM2 recombinant protein (Position: Q78-E398). Human TRIM2 shares 99.4% and 98.8% amino acid (aa) sequence identity with mouse and rat TRIM2, respectively.
-
-
anti-Tripartite Motif Containing 2 (TRIM2) (AA 1-100), (AA 1500-1600) antibody
TRIM2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Tripartite Motif Containing 2 (TRIM2) (C-Term) antibodyVerified TRIM2 适用: 人, 大鼠 WB, ELISA, FACS, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 2 (TRIM2) (AA 1-100), (AA 645-744) antibodyTRIM2 适用: 人, 大鼠 WB, FACS 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Tripartite Motif Containing 2 (TRIM2) (AA 1-100), (AA 645-744) antibodyTRIM2 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2B2 unconjugated
anti-Tripartite Motif Containing 2 (TRIM2) (AA 233-247) antibodyVerified TRIM2 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 2 (TRIM2) (AA 100-300) antibodyTRIM2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Balastik, M., Ferraguti, F., Pires-da Silva, A., Lee, T. H., Alvarez-Bolado, G., Lu, K. P., Gruss, P. Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration. Proc. Nat. Acad. Sci. 105: 12016-12021, 2008. 2. Nagase, T., Ishikawa, K., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 31-39, 1998. 3. Pehlivan, D., Coban Akdemir, Z., Karaca, E., Bayram, Y., Jhangiani, S., Yildiz, E. P., Muzny, D., Uluc, K., Gibbs, R. A., Baylor-Hopkins Center for Mendelian Genomics, Elcioglu, N., Lupski, J. R., Harel, T. Exome sequencing reveals homozygous TRIM2 mutation in a patient with early onset CMT and bilateral vocal cord paralysis. Hum. Genet. 134: 671-673, 2015. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- TRIM2 (Tripartite Motif Containing 2 (TRIM2))
-
别名
- TRIM2
-
背景
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.
-
分子量
- 82 kDa
-
基因ID
- 23321
-
UniProt
- Q9C040
抗原
-
