EED 抗体 (AA 77-441)
Quick Overview for EED 抗体 (AA 77-441) (ABIN7602442)
抗原
See all EED 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 77-441
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原理
- Anti-EED Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-EED Antibody Picoband® (ABIN7602442). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EED recombinant protein (Position: K77-R441).
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亚型
- IgG
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anti-Embryonic Ectoderm Development (EED) (N-Term) antibody
EED 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-100) antibodyEED 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 342-441) antibodyEED 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B12 unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 142-441) antibodyEED 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-300) antibodyEED 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 269-303) antibodyEED 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB51180 unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-441) antibodyEED 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 21-70) antibodyEED 适用: 人, 小鼠, 大鼠, 非洲爪蟾, 犬, Cow, 豚鼠, 马, 斑马鱼, 兔, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 1-300) antibodyEED 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Embryonic Ectoderm Development (EED) (AA 40-74), (N-Term) antibodyEED 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51500 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: EED embryonic ectoderm development". 2. Rietzler M, Bittner M, Kolanus W, Schuster A, Holzmann B (Nov 1998). "The human WD repeat protein WAIT-1 specifically interacts with the cytoplasmic tails of beta7-integrins". J. Biol. Chem. 273 (42): 27459-66. 3. Schumacher A, Lichtarge O, Schwartz S, Magnuson T (Jan 1999). "The murine Polycomb-group gene eed and its human orthologue: functional implications of evolutionary conservation". Genomics 54(1): 79-88. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- EED (Embryonic Ectoderm Development (EED))
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别名
- EED
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背景
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Synonyms: Metabotropic glutamate receptor 5, mGluR5, GRM5, GPRC1E, MGLUR5
Tissue Specificity: Isoform 1 and isoform 2 are detected in bone marrow cells, spermatogonia and spermatocytes, but not in round spermatids, elongating spermatids and spermatozoa. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa, but not in spermatogonia and spermatocytes (at protein level). Isoform 1 is widely expressed and detected in fetal liver and bone marrow. Isoform 3 is detected in bone marrow cells enriched in hematopoietic stem cells.
Background: Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. Furthermore, this protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
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分子量
- 70 kDa
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基因ID
- 8726
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UniProt
- O75530
抗原
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