RAE1 抗体 (AA 76-368)
Quick Overview for RAE1 抗体 (AA 76-368) (ABIN7602428)
抗原
See all RAE1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 76-368
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                                            原理
- Anti-RAE1 Antibody Picoband®
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                                            交叉反应 (详细)
- No cross-reactivity with other proteins.
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                                            产品特性
- Anti-RAE1 Antibody Picoband® (ABIN7602428). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- E.coli-derived human RAE1 recombinant protein (Position: Q76-K368).
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                                            亚型
- IgG
 
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                                            应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human, Rat
 Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
 Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 ELISA, 0.1-0.5 μg/mL, -
 1. Bharathi, A., Ghosh, A., Whalen, W. A., Yoon, J. H., Pu, R., Dasso, M., Dhar, R. The human RAE1 gene is a functional homologue of Schizosaccharomyces pombe rae1 gene involved in nuclear export of poly(A)+ RNA. Gene 198: 251-258, 1997. 2. Jeganathan, K. B., Malureanu, L., van Deursen, J. M. The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. Nature 438: 1036-1039, 2005. 3. Kraemer, D., Blobel, G. mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm. Proc. Nat. Acad. Sci. 94: 9119-9124, 1997.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
 
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    - RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
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                                            别名
- RAE1
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                                            背景
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                        Synonyms: Mucosal addressin cell adhesion molecule 1, MAdCAM-1, hMAdCAM-1, MADCAM1 Tissue Specificity: Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney or peripheral blood leukocytes. Background: mRNA export factor is a protein that in humans is encoded by the RAE1 gene. Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in ly or inly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. 
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                                            分子量
- 41 kDa
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                                            基因ID
- 8480
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                                            UniProt
- P78406
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                                            途径
- SARS-CoV-2 Protein Interactome
 抗原
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