HCCS 抗体 (AA 76-268)
Quick Overview for HCCS 抗体 (AA 76-268) (ABIN7602424)
抗原
See all HCCS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-268
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原理
- Anti-HCCS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-HCCS Antibody Picoband® (ABIN7602424). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HCCS recombinant protein (Position: K76-S268).
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亚型
- IgG
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anti-Holocytochrome C Synthase (HCCS) (AA 1-268) antibody
HCCS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) antibodyHCCS 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) (AA 1-268) antibodyHCCS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) antibodyHCCS 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) (AA 1-268) antibodyHCCS 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Holocytochrome C Synthase (HCCS) (AA 1-268) antibodyHCCS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) (Center) antibodyHCCS 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) (AA 81-130) antibodyHCCS 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibodyHCCS 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Holocytochrome C Synthase (HCCS) (AA 51-150) antibodyHCCS 适用: 小鼠, 大鼠 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Indrieri, A., Conte, I., Chesi, G., Romano, A., Quartararo, J., Tate, R., Ghezzi, D., Zeviani, M., Goffrini, P., Ferrero, I., Bovolenta, P., Franco, B. The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes. EMBO Molec. Med. 5: 280-293, 2013. Note: Erratum: EMBO Molec. Med. 6: 849 only, 2014. 2. Morleo, M., Pramparo, T., Perone, L., Gregato, G., Le Caignec, C., Mueller, R. F., Ogata, T., Raas-Rothschild, A., de Blois, M. C., Wilson, L. C., Zaidman, G., Zuffardi, O., Ballabio, A., Franco, B. Microphthalmia with linear skin defects (MLS) syndrome: clinical, cytogenetic, and molecular characterization of 11 cases. Am. J. Med. Genet. 137A: 190-198, 2005. 3. Prakash, S. K., Cormier, T. A., McCall, A. E., Garcia, J. J., Sierra, R., Haupt, B., Zoghbi, H. Y., Van den Veyver, I. B. Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome. Hum. Molec. Genet. 11: 3237-3248, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HCCS (Holocytochrome C Synthase (HCCS))
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别名
- HCCS
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背景
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Synonyms: Insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1, Igfbp1, Igfbp-1,
Tissue Specificity: High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.
Background: Cytochrome c-type heme lyase is an enzyme that in humans is encoded by the HCCS gene on chromosome X. The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
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分子量
- 31 kDa
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基因ID
- 3052
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UniProt
- P53701
抗原
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