GGCX 抗体 (AA 75-730)
Quick Overview for GGCX 抗体 (AA 75-730) (ABIN7602419)
抗原
See all GGCX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-730
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原理
- Anti-GGCX Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GGCX Antibody Picoband® (ABIN7602419). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GGCX recombinant protein (Position: M75-A730).
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亚型
- IgG
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anti-gamma-Glutamyl Carboxylase (GGCX) antibody
GGCX 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (C-Term) antibodyVerified GGCX 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (Middle Region) antibodyGGCX 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (AA 383-526) antibodyGGCX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (AA 533-629) antibodyGGCX 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (AA 684-733) antibodyGGCX 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (AA 479-758) antibodyGGCX 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (AA 548-578) antibodyGGCX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19281 unconjugated
anti-gamma-Glutamyl Carboxylase (GGCX) (AA 555-585), (Middle Region) antibodyGGCX 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Brenner, B., Sanchez-Vega, B., Wu, S.-M., Lanir, N., Stafford, D. W., Solera, J. A missense mutation in a gamma-glutamyl carboxylase gene causes combined deficiency of all vitamin K-dependent blood coagulation factors. Blood 92: 4554-4559, 1998. 2. Brenner, B., Tavori, S., Zivelin, A., Keller, C. B., Suttie, J. W., Tatarsky, I., Seligsohn, U. Hereditary deficiency of all vitamin K-dependent procoagulants and anticoagulants. Brit. J. Haemat. 75: 537-542, 1990. 3. Kuo, W.-L., Stafford, D. W., Cruces, J., Gray, J., Solera, J. Chromosomal localization of the gamma-glutamyl carboxylase gene at 2p12. Genomics 25: 746-748, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GGCX (gamma-Glutamyl Carboxylase (GGCX))
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别名
- GGCX
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背景
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Synonyms: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP, DPT
Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.
Background: Gamma-glutamyl carboxylase is an enzyme that in humans is encoded by the GGCX gene, located on chromosome 2 at 2p12. This gene encodes an integral membrane protein of the rough endoplasmic reticulum that carboxylates glutamate residues of vitamin K-dependent proteins to gamma carboxyl glutamate, a modification that is required for their activity. The vitamin K-dependent protein substrates have a propeptide that binds the enzyme, with carbon dioxide, dioxide, and reduced vitamin K acting as co-substrates. Vitamin K-dependent proteins affect a number of physiologic processes including blood coagulation, prevention of vascular calcification, and inflammation. Allelic variants of this gene have been associated with pseudoxanthoma elasticum-like disorder with associated multiple coagulation factor deficiency. Alternative splicing results in multiple transcript variants.
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分子量
- 88 kDa
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基因ID
- 2677
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UniProt
- P38435
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途径
- SARS-CoV-2 Protein Interactome
抗原
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