GLUL 抗体 (AA 74-373)
Quick Overview for GLUL 抗体 (AA 74-373) (ABIN7602403)
抗原
See all GLUL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 74-373
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原理
- Anti-GLUL Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-GLUL Antibody Picoband® (ABIN7602403). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GLUL recombinant protein (Position: N74-N373).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clancy, K. P., Berger, R., Cox, M., Bleskan, J., Walton, K. A., Hart, I., Patterson, D. Localization of the L-glutamine synthetase gene to chromosome 1q23. Genomics 38: 418-420, 1996. 2. Eelen, G., Dubois, C., Cantelmo, A. R., Goveia, J., Bruning, U., DeRan, M., Jarugumilli, G., van Rijssel, J., Saladino, G., Comitani, F., Zecchin, A., Rocha, S., and 27 others. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature 561: 63-69, 2018. 3. Gibbs, C. S., Campbell, K. E., Wilson, R. H. Sequence of a human glutamine synthetase cDNA. Nucleic Acids Res. 15: 6293 only, 1987. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GLUL (Glutamate-Ammonia Ligase (GLUL))
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别名
- GLUL
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背景
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Synonyms: ETS-related transcription factor Elf-1, E74-like factor 1, ELF1
Tissue Specificity: In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.
Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.
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分子量
- 42 kDa
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基因ID
- 2752
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UniProt
- P15104
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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