RREB1 抗体 (AA 732-1559)
Quick Overview for RREB1 抗体 (AA 732-1559) (ABIN7602395)
抗原
See all RREB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 732-1559
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原理
- Anti-RREB1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RREB1 Antibody Picoband® (ABIN7602395). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RREB1 recombinant protein (Position: K732-Q1559).
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亚型
- IgG
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anti-Ras Responsive Element Binding Protein 1 (RREB1) antibody
RREB1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Responsive Element Binding Protein 1 (RREB1) antibodyRREB1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Carson, E. B., McMahon, M., Baylin, S. B., Nelkin, B. D. Ret gene silencing is associated with Raf-1-induced medullary thyroid carcinoma cell differentiation. Cancer Res. 55: 2048-2052, 1995. 2. Flajollet, S., Poras, I., Carosella, E. D., Moreau, P. RREB-1 is a transcriptional repressor of HLA-G. J. Immun. 183: 6948-6959, 2009. 3. Kent, O. A., Saha, M., Coyaud, E., Burston, H. E., Law, N., Dadson, K., Chen, S., Laurent, E. M., St-Germain, J., Sun, R. X., Matsumoto, Y., Cowen, J., and 10 others. Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes. Nature Commun. 11: 4673, 2020. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RREB1 (Ras Responsive Element Binding Protein 1 (RREB1))
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别名
- RREB1
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背景
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Synonyms: Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Tissue Specificity: Pancreas-specific (at protein level). Loss of expression is seen in ductal type pancreas cancers.
Background: Ras-responsive element-binding protein 1 is a protein that in humans is encoded by the RREB1 gene. The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene.
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分子量
- 160 kDa
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基因ID
- 6239
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UniProt
- Q92766
抗原
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