MAEL 抗体 (AA 73-347)
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北京 101111
Quick Overview for MAEL 抗体 (AA 73-347) (ABIN7602386)
抗原
See all MAEL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 73-347
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原理
- Anti-MAEL Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MAEL Antibody (ABIN7602386). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MAEL recombinant protein (Position: E73-Q347).
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亚型
- IgG
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anti-Maelstrom Spermatogenic Transposon Silencer (MAEL) (AA 1-200) antibody
MAEL 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))
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别名
- MAEL
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背景
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Synonyms: FERM domain-containing protein 6, Willin, FRMD6, C14orf31
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
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分子量
- 49 kDa
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基因ID
- 84944
抗原
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