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ETV5 抗体 (AA 72-246)

This anti-ETV5 antibody is a 兔 多克隆 antibody detecting ETV5 in WB, ELISA, FACS, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7602370
发货至: 中国

Quick Overview for ETV5 抗体 (AA 72-246) (ABIN7602370)

抗原

See all ETV5 抗体
ETV5 (Ets Variant 5 (ETV5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ETV5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    AA 72-246

    原理

    Anti-ERM/Etv5 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ERM/Etv5 Antibody Picoband® (ABIN7602370). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ERM/Etv5 recombinant protein (Position: D72-Q246).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chen, C., Ouyang, W., Grigura, V., Zhou, Q., Carnes, K., Lim, H., Zhao, G.-Q., Arber, S., Kurpios, N., Murphy, T. L., Cheng, A. M., Hassell, J. A., Chandrashekar, V., Hofmann, M.-C., Hess, R. A., Murphy, K. M. ERM is required for transcriptional control of the spermatogonial stem cell niche. (Letter) Nature 436: 1030-1034, 2005. 2. Lu, B. C., Cebrian, C., Chi, X., Kuure, S., Kuo, R., Bates, C. M., Arber, S., Hassell, J., MacNeil, L., Hoshi, M., Jain, S., Asai, N., Takahashi, M., Schmidt-Ott, K. M., Barasch, J., D'Agati, V., Costantini, F. Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis. Nature Genet. 41: 1295-1302, 2009. Note: Erratum: Nature Genet. 42: 361 only, 2010. 3. Monte, D., Baert, J. L., Defossez, P. A., de Launoit, Y., Stehelin, D. Molecular cloning and characterization of human ERM, a new member of the Ets family closely related to mouse PEA3 and ER81 transcription factors. Oncogene 9: 1397-1406, 1994.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ETV5 (Ets Variant 5 (ETV5))

    别名

    ETV5

    背景

    Synonyms: Glutamate receptor ionotropic, NMDA 1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, GRIN1, NMDAR1

    Tissue Specificity: Widely expressed, with strongest expression in placenta (at protein level). Secreted by synovial fibroblasts. Up- regulated in osteoarthritis and rheumatoid arthritis synovial fluids and cartilage as compared with non-arthritic (at protein level).

    Background: Ets variant 5 (ETV5) (also named ERM transcription factor) is a transcription factor that in humans is encoded by the ETV5 gene. It is generated in Sertoli cells, which are found in the testes and play a crucial role in spermatogenesis. Its ortholog has been linked to both obesity and bipolar disorder.

    分子量

    70 kDa

    基因ID

    2119

    UniProt

    P41161

    途径

    Synaptic Membrane, Skeletal Muscle Fiber Development
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