Spectrin beta Chain, Erythrocyte (SPTB) (AA 703-2137) 抗体
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- 抗原 See all Spectrin beta Chain, Erythrocyte (SPTB) 抗体
- Spectrin beta Chain, Erythrocyte (SPTB)
- 抗原表位
- AA 703-2137
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- Anti-beta 1 Spectrin/SPTB Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-beta 1 Spectrin/SPTB Antibody Picoband® (ABIN7602356). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human beta 1 Spectrin/SPTB recombinant protein (Position: M703-Y2137).
- 亚型
- IgG
- Top Product
- Discover our top product SPTB Primary Antibody
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anti-Spectrin beta Chain, Erythrocyte (SPTB) antibody
SPTB 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal RG-26 unconjugated
anti-Spectrin beta Chain, Erythrocyte (SPTB) antibodySPTB 适用: 人 WB, IP, IHC 宿主: 小鼠 Monoclonal DB2 unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Basseres, D. S., Duarte, A. S. S., Hassoun, H., Costa, F. F., Saad, S. T. O. Beta-spectrin S-ta Barbara: a novel frameshift mutation in hereditary spherocytosis associated with detectable levels of mRNA and a germ cell line mosaicism. Brit. J. Haemat. 115: 347-353, 2001. Note: Erratum: Brit. J. Haemat. 116: 925 only, 2002. 2. Basseres, D. S., Vicentim, D. L., Costa, F. F., Saad, S. T. O., Hassoun, H. Beta-spectrin Promissao: a translation initiation codon mutation of the beta-spectrin gene (ATG-to-GTG) associated with hereditary spherocytosis and spectrin deficiency in a Brazilian family. (Letter) Blood 91: 368-369, 1998. 3. Becker, P. S., Tse, W. T., Lux, S. E., Forget, B. G. Beta-spectrin Kissimmee: a spectrin variant associated with autosomal dominant hereditary spherocytosis and defective binding to protein 4.1. J. Clin. Invest. 92: 612-616, 1993. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- Spectrin beta Chain, Erythrocyte (SPTB)
- 别名
- SPTB (SPTB 产品)
- 背景
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Synonyms: Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1, Caspase-2 subunit p18, Caspase-2 subunit p13, Caspase-2 subunit p12, CASP2, ICH1, NEDD2
Tissue Specificity: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Background: Spectrin beta chain, erythrocyte is a protein that in humans is encoded by the SPTB gene. This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.
- 分子量
- 270 kDa
- 基因ID
- 6710
- UniProt
- P11277
- 途径
- Regulation of Actin Filament Polymerization
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