电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IL1RL1 抗体 (AA 70-556)

This anti-IL1RL1 antibody is a 兔 多克隆 antibody detecting IL1RL1 in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN7602351
发货至: 中国

Quick Overview for IL1RL1 抗体 (AA 70-556) (ABIN7602351)

抗原

See all IL1RL1 抗体
IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

适用

  • 60
  • 10
  • 2
  • 2
  • 1

宿主

  • 41
  • 15
  • 4
  • 1
  • 1
  • 1

克隆类型

  • 43
  • 20
多克隆

标记

  • 43
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL1RL1 antibody is un-conjugated

应用范围

  • 43
  • 22
  • 16
  • 13
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-556

    原理

    Anti-ST2/IL1RL1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ST2/IL1RL1 Antibody Picoband® (ABIN7602351). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ST2/IL1RL1 recombinant protein (Position: Q70-Q556).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Brint, E. K., Xu, D., Liu, H., Dunne, A., McKenzie, A. N. J., O'Neill, L. A. J., Liew, F. Y. ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nature Immun. 5: 373-379, 2004. 2. Buckley, J. M., Liu, J. H., Li, C. H., Blankson, S., Wu, Q. D., Jiang, Y., Redmond, H. P., Wang, J. H. Increased susceptibility of ST2-deficient mice to polymicrobial sepsis is associated with an impaired bactericidal function. J. Immun. 187: 4293-4299, 2011. 3. Chackerian, A. A., Oldham, E. R., Murphy, E. E., Schmitz, J., Pflanz, S., Kastelein, R. A. IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex. J. Immun. 179: 2551-2555, 2007.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

    别名

    IL1RL1

    背景

    Synonyms: Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk, SYK

    Tissue Specificity: Widely expressed in hematopoietic cells. Expressed in neutrophils. Within the B-cell compartment, expressed from pro- and pre-B cells to plasma cells.

    Background: Interleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a protein that in humans is encoded by the IL1RL1 gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

    分子量

    70 kDa

    基因ID

    9173

    UniProt

    Q01638
You are here:
Chat with us!