SCARB1 抗体 (AA 70-492)
Quick Overview for SCARB1 抗体 (AA 70-492) (ABIN7602350)
抗原
See all SCARB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-492
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原理
- Anti-Scavenging Receptor SR-BI/SCARB1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Scavenging Receptor SR-BI/SCARB1 Antibody Picoband® (ABIN7602350). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Scavenging Receptor SR-BI/SCARB1 recombinant protein (Position: F70-R492).
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亚型
- IgG
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anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 21-100) antibody
SCARB1 适用: 人, 大鼠, 小鼠, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 450-509), (C-Term) antibodySCARB1 适用: 人, 大鼠, 小鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 33-440) antibodySCARB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (Internal Region) antibodySCARB1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 238-250) antibodyVerified SCARB1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 1-100) antibodySCARB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 33-443) antibodySCARB1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (C-Term) antibodyVerified SCARB1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Scavenger Receptor Class B, Member 1 (SCARB1) (AA 114-163) antibodySCARB1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: SCARB1 Scavenger receptor class B, member 1". 2. Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M (January 1996). "Identification of scavenger receptor SR-BI as a high density lipoprotein receptor".Science 271 (5248): 518-20. 3. Duggan AE, Marie RS, Callard IP (April 2002). "Expression of SR-BI (Scavenger Receptor Class B Type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates". J. Exp. Zool.292 (5): 430-4. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
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别名
- SCARB1
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背景
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Synonyms: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform,PI3-kinase subunit beta,PI3K-beta,PI3Kbeta,PtdIns-3-kinase subunit beta,2.7.1.153,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta,PtdIns-3-kinase subunit p110-beta,p110beta,PIK3CB,PIK3C1,
Tissue Specificity: Expressed ubiquitously.
Background: Scavenger receptor class B member 1 (SRB1), also known as SR-BI, is a protein that in humans is encoded by the SCARB1 gene. SR-BI functions as a receptor for high-density lipoprotein. Scavenger receptor class B, type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. It is best known for its role in facilitating the uptake of cholesteryl esters from high-density lipoproteins in the liver. This process drives the movement of cholesterol from peripheral tissues towards the liver for excretion. This movement of cholesterol is known as reverse cholesterol transport and is a protective mechanism against the development of atherosclerosis, which is the principal cause of heart disease and stroke. SR-BI has also been identified in the livers of non-mammalian species (turtle, goldfish, shark, chicken, frog, and skate), suggesting it emerged early in vertebrate evolutionary history. The turtle also seems to upregulate SB-RI during egg development, indicating that cholesterol efflux may be at peak levels during developmental stages.
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分子量
- 85 kDa
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基因ID
- 949
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途径
- Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
抗原
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