HOXC13 抗体 (AA 7-155)
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- 抗原 See all HOXC13 products
- HOXC13 (Homeobox C13 (HOXC13))
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抗原表位
- AA 7-155
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HOXC13 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 原理
- Anti-HOXC13 Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins.
- 产品特性
- Anti-HOXC13 Antibody Picoband® (ABIN7602314). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human HOXC13 recombinant protein (Position: L7-E155).
- 亚型
- IgG
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Farooq, M., Kurban, M., Fujimoto, A., Fujikawa, H., Abbas, O., Nemer, G., Saliba, J., Sleiman, R., Tofaili, M., Kibbi, A.-G., Ito, M., Shimomura, Y. A homozygous frameshift mutation in the HOXC13 gene underlies pure hair and nail ectodermal dysplasia in a Syrian family. Hum. Mutat. 34: 578-581, 2013. 2. Godwin, A. R., Capecchi, M. R. Hoxc13 mutant mice lack external hair. Genes Dev. 12: 11-20, 1998. 3. Lin, Z., Chen, Q., Shi, L., Lee, M., Giehl, K. A., Tang, Z., Wang, H., Zhang, J., Yin, J., Wu, L., Xiao, R., Liu, X., Dai, L., Zhu, X., Li, R., Betz, R. C., Zhang, X., Yang, Y. Loss-of-function mutations in HOXC13 cause pure hair and nail ectodermal dysplasia. Am. J. Hum. Genet. 91: 906-911, 2012. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- HOXC13 (Homeobox C13 (HOXC13))
- 别名
- HOXC13 (HOXC13 产品)
- 背景
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Synonyms: Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15, ATP-dependent RNA helicase #46, DEAH box protein 15, DHX15, DBP1, DDX15
Tissue Specificity: Ubiquitous.
Background: Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.
- 分子量
- 35 kDa
- 基因ID
- 3229
- UniProt
- P31276
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