DR1 抗体 (AA 7-154)
Quick Overview for DR1 抗体 (AA 7-154) (ABIN7602313)
抗原
See all DR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-154
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原理
- Anti-DR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DR1 Antibody Picoband® (ABIN7602313). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DR1 recombinant protein (Position: N7-A154).
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亚型
- IgG
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anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) antibody
DR1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) antibodyDR1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) antibodyDR1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) antibodyDR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (N-Term) antibodyDR1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 小鸡, 斑马鱼, 马, 兔, 豚鼠, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 63-112) antibodyDR1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 小鸡, 斑马鱼, 马, 兔, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (N-Term) antibodyDR1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 83-112) antibodyDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37581 unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 83-112) antibodyDR1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Goppelt, A., Stelzer, G., Lottspeich, F., Meisterernst, M. A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains. EMBO J. 15: 3105-3116, 1996. 2. Inostroza, J. A., Mermeistein, F. H., Ha, I., Lane, W. S., Reinberg, D. Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription. Cell 70: 477-489, 1992. 3. Kamada, K., Shu, F., Chen, H., Malik, S., Stelzer, G., Roeder, R. G., Meisterernst, M., Burley, S. K. Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex. Cell 106: 71-81, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
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别名
- DR1
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背景
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Synonyms: Cone-rod homeobox protein,CRX,CORD2,
Tissue Specificity: Retina.
Background: Protein Dr1 is a protein that in humans is encoded by the DR1 gene. This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
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分子量
- 19 kDa
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基因ID
- 1810
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UniProt
- Q01658
抗原
-
