DLAT 抗体 (AA 69-642)
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北京 101111
Quick Overview for DLAT 抗体 (AA 69-642) (ABIN7602307)
抗原
See all DLAT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 69-642
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原理
- Anti-DLAT Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-DLAT Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DLAT recombinant protein (Position: P69-P642).
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亚型
- IgG
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anti-Dihydrolipoyl Transacetylase (DLAT) (AA 368-626) antibody
DLAT 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyKD Validated DLAT 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB805 unconjugated Recombinant Antibody
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyDLAT 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 87-270) antibodyDLAT 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-647) antibodyDLAT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 1-647) antibodyDLAT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 579-607), (C-Term) antibodyDLAT 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26843 unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) antibodyDLAT 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 61-110) antibodyDLAT 适用: 人, 小鼠, 大鼠, 兔, 犬, 斑马鱼, Cow, 豚鼠, 马, Pig, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dihydrolipoyl Transacetylase (DLAT) (AA 26-217) antibodyDLAT 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- DLAT (Dihydrolipoyl Transacetylase (DLAT))
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别名
- DLAT
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背景
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Background: Dihydrolipoyl transacetylase (or dihydrolipoamide acetyltransferase) is an enzyme component of the multienzyme pyruvate dehydrogenase complex. This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.
Gene Full Name: dihydrolipoamide S-acetyltransferase
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分子量
- 69 kDa
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基因ID
- 1737
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UniProt
- P10515
抗原
-
