NSMCE4A 抗体 (AA 69-380)
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北京 101111
Quick Overview for NSMCE4A 抗体 (AA 69-380) (ABIN7602302)
抗原
See all NSMCE4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 69-380
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原理
- Anti-NSMCE4A Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-NSMCE4A Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NSMCE4A recombinant protein (Position: D69-Q380).
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亚型
- IgG
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anti-Non-SMC Element 4 Homolog A (NSMCE4A) (AA 29-57), (N-Term) antibody
NSMCE4A 适用: 人 WB 宿主: 兔 Polyclonal RB24938 unconjugated
anti-Non-SMC Element 4 Homolog A (NSMCE4A) (C-Term) antibodyNSMCE4A 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
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别名
- NSMCE4A
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背景
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Background: Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene. NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
Gene Full Name: NSE4A component of SMC5/6 complex
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分子量
- 50 kDa
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基因ID
- 54780
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UniProt
- Q9NXX6
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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