NSMCE4A 抗体 (AA 69-380)
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- 抗原 See all NSMCE4A 抗体
- NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
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抗原表位
- AA 69-380
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NSMCE4A antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- Anti-NSMCE4A Antibody Picoband®
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Anti-NSMCE4A Antibody Picoband® (ABIN7602302). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human NSMCE4A recombinant protein (Position: D69-Q380).
- 亚型
- IgG
- Top Product
- Discover our top product NSMCE4A Primary Antibody
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anti-Non-SMC Element 4 Homolog A (NSMCE4A) (C-Term) antibody
NSMCE4A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Non-SMC Element 4 Homolog A (NSMCE4A) (AA 29-57), (N-Term) antibodyNSMCE4A 适用: 人 WB 宿主: 兔 Polyclonal RB24938 unconjugated
anti-Non-SMC Element 4 Homolog A (NSMCE4A) (AA 36-65), (N-Term) antibodyNSMCE4A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hu, B., Liao, C., Millson, S. H., Mollapour, M., Prodromou, C., Pearl, L. H., Piper, P. W., Panaretou, B. Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex. Molec. Microbiol. 55: 1735-1750, 2005. 2. Taylor, E. M., Copsey, A. C., Hudson, J. J. R., Vidot, S., Lehmann, A. R. Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex. Molec. Cell. Biol. 28: 1197-1206, 2008. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))
- 别名
- NSMCE4A (NSMCE4A 产品)
- 背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene. NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.
- 分子量
- 50 kDa
- 基因ID
- 54780
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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