GANAB 抗体 (AA 68-944)
Quick Overview for GANAB 抗体 (AA 68-944) (ABIN7602292)
抗原
See all GANAB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 68-944
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原理
- Anti-GANAB Antibody Picoband®
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产品特性
- Anti-GANAB Antibody Picoband® (ABIN7602292). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GANAB recombinant protein (Position: Q68-R944). Human GANAB shares 92% amino acid (aa) sequence identity with mouse GANAB.
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anti-Glucosidase, Alpha, Neutral AB (GANAB) (AA 1-944) antibody
GANAB 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (N-Term) antibodyGANAB 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (AA 1-260) antibodyGANAB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (AA 428-540) antibodyGANAB 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) antibodyGANAB 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (AA 1-944) antibodyGANAB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (C-Term) antibodyGANAB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (AA 865-957) antibodyGANAB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (C-Term) antibodyGANAB 适用: 人, 小鼠, 大鼠, Cow, Pig, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Alpha, Neutral AB (GANAB) (AA 47-251) antibodyGANAB 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Besse, W., Choi, J., Ahram, D., Mane, S., Sanna-Cherchi, S., Torres, V., Somlo, S. A noncoding variant in GANAB explains isolated polycystic liver disease (PCLD) in a large family. Hum. Mutat. 39: 378-382, 2018. 2. Martiniuk, F., Smith, M., Desnick, R., Astrin, K., Mitra, J., Hirschhorn, R. Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11. (Abstract) Am. J. Hum. Genet. 34: 173A only, 1982. 3. Martiniuk, F., Smith, M., Ellenbogen, A., Desnick, R. J., Astrin, K., Mitra, J., Hirschhorn, R. Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11. Cytogenet. Cell Genet. 35: 110-116, 1983. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GANAB (Glucosidase, Alpha, Neutral AB (GANAB))
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别名
- GANAB
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背景
- Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene. This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.
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分子量
- 100 kDa
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基因ID
- 23193
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UniProt
- Q14697
抗原
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