TCF12 抗体 (AA 67-300)
Quick Overview for TCF12 抗体 (AA 67-300) (ABIN7602265)
抗原
See all TCF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 67-300
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原理
- Anti-HEB/TCF12 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-HEB/TCF12 Antibody Picoband® (ABIN7602265). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HEB/TCF12 recombinant protein (Position: S67-G300). Human TCF12 shares 96.6% amino acid (aa) sequence identity with both mouse and rat TCF12.
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亚型
- IgG
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anti-Transcription Factor 12 (TCF12) (AA 364-453) antibody
TCF12 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E9 unconjugated
anti-Transcription Factor 12 (TCF12) (AA 443-682) antibodyTCF12 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (N-Term) antibodyTCF12 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (N-Term) antibodyTCF12 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (N-Term) antibodyTCF12 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 犬, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (N-Term) antibodyTCF12 适用: 人, 小鼠, Cow, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (AA 504-553) antibodyTCF12 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 犬, Pig, 马, Hamster, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (N-Term) antibodyTCF12 适用: 人, 大鼠, 小鼠, Cow, Pig, 小鸡, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Transcription Factor 12 (TCF12) (AA 443-682) antibodyTCF12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Davis, E. E., Balasubramanian, R., Kupchinsky, Z. A., Keefe, D. L., Jr., Plummer, L., Khan, K., Meczekalski, B., Heath, K. E., Lopez-Gonzalez, V., Ballesta-Martinez, M. J., Margabanthu, G., Price, S., and 12 others. TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci. Hum. Molec. Genet. 29: 2435-2450, 2020. 2. Doyle, K., Zhang, Y., Baer, R., Bina, M. Distinguishable patterns of protein-DNA interactions involving complexes of basic helix-loop-helix proteins. J. Biol. Chem. 269: 12099-12105, 1994. 3. Gan, T.-I., Rowen, L., Nesbitt, R., Roe, B. A., Wu, H., Hu, P., Yao, Z., Kim, U.-J., O'Sickey, T., Bina, M. Genomic organization of human TCF12 gene and spliced mRNA variants producing isoforms of transcription factor HTF4. Cytogenet. Genome Res. 98: 245-248, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TCF12 (Transcription Factor 12 (TCF12))
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别名
- TCF12
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背景
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Synonyms: TCF12, BHLHB20, HEB, HTF4, Transcription factor 12, TCF-12, Class B basic helix-loop-helix protein 20, bHLHb20, DNA-binding protein HTF4, E-box-binding protein, Transcription factor HTF-4
Background: Transcription factor 12 is a protein that in humans is encoded by the TCF12 gene. The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
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分子量
- 85 kDa
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基因ID
- 6938
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UniProt
- Q99081
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途径
- SARS-CoV-2 Protein Interactome
抗原
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